Epidemiology and Diagnosis of Mucormycosis: An Update

Mucormycosis is a fungal infection angioinvasive, because fungi of the Mucorales order. incidents that can not be measured precisely, because there are few population-based studies, but some studies have shown that it increases. Mucormycosis prevalence in India is approximately 80 times the prevalence in developed countries, to about 0.14 cases per 1000 population. Diabetes mellitus is a major underlying disease globally, especially in low- and middle-countries. In developed countries the underlying disease is the most common hematologic malignancy and transplantation.

Τhe mucormycosis epidemiology evolved as a new immunomodulatory agent used in the treatment of cancer and autoimmune diseases, and as a modern diagnostic tools lead to earlier identification of rare genera / species like Apophysomyces or Saksenaea complex. Additionally, new risk factors reported from Asia, including post-pulmonary tuberculosis and chronic kidney disease. New species arise including Rhizopus homothallicus, Thamnostylum lucknowense, irregularis Mucor and Saksenaea erythrospora. Diagnosis remains of mucormycosis challenging. Clinical approach to diagnosis has a sensitivity and low specificity, but helps in increasing suspicion and encourage initiation of laboratory testing.

Histopathology, direct examination and culture remain important tools, although improved molecular methods. Internal transcribed spacer region (ITS) is the most widely sequencing of DNA regions of the fungus and is recommended as first-line method for the identification of the species Mucorales. new molecular platform that is being investigated and new genetic targets mushrooms are being explored. molecular-based methods have gained acceptance to confirm infection when applied to the network. Mucorales detection method on the DNA in the blood have shown promising results for the early diagnosis and quick and can be used as a screening test in high-risk patients, but it has been validated in clinical studies. More, much needed, fast method that does not require invasive procedures, such as breath test metabolomics-based point-of-care, or based on serology, are being developed and hopefully will be evaluated in the near future.

Clinical analysis of network-connected nature expresses markers of psoriasis treatment of active transcription with Liangxue-Jiedu decoction

Ethnopharmacological relevance: Psoriasis is a recurrent inflammatory skin disease complex with different pathological changes in various stages. Psoriasis in the active phase, which is comparable to the kind of blood-heat in traditional Chinese medicine (TCM), has been conventionally treated by Liangxue Jiedu decoction (LJD) in TCM for decades with proven success. According to TCM theory, LJD has the function of removing heat and pathogenic factors from the blood.

The purpose of this research: We aimed to determine the molecular features associated with blood-heat syndrome active psoriasis and to identify genes respond to treatment LJD accompanied by a lesion remission.
Materials and methods: healthy volunteers and patients with psoriasis who meet the diagnostic criteria specifically recruited. Twenty-six profiled transcriptome of cells of peripheral blood mononuclear (PBMC) from 10 patients with psoriasis (pre- and post-treatment) and 6 healthy volunteers.

Data sequencing RNA is analyzed using an integrated approach which combines differential analysis of gene expression (DGEA) and network analysis of gene co-expression of weighted (WGCNA), where the expression of genes associated with some clinical characteristics, including the psoriasis and severity index (PASI), and the increased rate of skin lesions (ΔPASI). LJD action then verified using in vitro cell assay combined flow cytometric analysis and RT-PCR.

Zika Virus prM Protein (African) control for Western blot
ZPRM11-C	Alpha Diagnostics	100 ul	EUR 343.2

Goat IgG (-ve control for flow cytometry) (isotype control)
20011-100	Alpha Diagnostics	100 test	EUR 123.6

Mayaro virus (MAYV) 6K Protein control for Western Blotting
MAYV51-C	Alpha Diagnostics	100 ug	EUR 343.2

Mayaro virus (MAYV) E3 protein control for Western Blotting
MAYV61-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Nipah virus Glycoprotein control for Western Blotting
NIV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Mayaro virus (MAYV) nsP1 protein control for Western Blotting
MAYV41-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Nipah virus Nucleoprotein control for Western Blotting
NIV21-C	Alpha Diagnostics	100 ul	EUR 270

BSA Control for Age-BSA
2221-BSA	Biovision	each	EUR 210

BSA Control for AGE-BSA
35R-AA007	Fitzgerald	10 mg	EUR 268.8
Description: BSA Control for AGE protein (BSA modified), Cat No. 30R-AA007

NATtrol Respiratory Panel 2.1 (RP2.1) Controls (12 x 0.3mL)
NATRPC2.1-BIO	Zeptometrix	12 x 0.3mL	EUR 529

Mayaro virus (MAYV) Capsid Protein control for Western Blotting
MAYV31-C	Alpha Diagnostics	100 ul	EUR 343.2

AAV1 Null Control Virus
AAV-351	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 1.

AAV2 Null Control Virus
AAV-352	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 2.

AAV3 Null Control Virus
AAV-353	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 3.

AAV4 Null Control Virus
AAV-354	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 4.

AAV5 Null Control Virus
AAV-355	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 5.

AAV6 Null Control Virus
AAV-356	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 6.

AAV1-GFP Control Virus
AAV-301	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 1.

AAV2-GFP Control Virus
AAV-302	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 2.

AAV3-GFP Control Virus
AAV-303	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 3.

AAV4-GFP Control Virus
AAV-304	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 4.

AAV5-GFP Control Virus
AAV-305	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 5.

AAV6-GFP Control Virus
AAV-306	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 6.

AAV2-Cre Control Virus
AAV-310	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 2.

AAV1-Cre Control Virus
AAV-311	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 1.

AAV3-Cre Control Virus
AAV-313	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 3.

AAV4-Cre Control Virus
AAV-314	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 4.

AAV5-Cre Control Virus
AAV-315	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 5.

AAV6-Cre Control Virus
AAV-316	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 6.

AAV2-Luc Control Virus
AAV-320	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 2.

AAV1-Luc Control Virus
AAV-321	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 1.

AAV3-Luc Control Virus
AAV-323	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 3.

AAV4-Luc Control Virus
AAV-324	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 4.

AAV5-Luc Control Virus
AAV-325	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 5.

AAV6-Luc Control Virus
AAV-326	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 6.

AAV1-LacZ Control Virus
AAV-341	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 1.

AAV2-LacZ Control Virus
AAV-342	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 2.

AAV3-LacZ Control Virus
AAV-343	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 3.

AAV4-LacZ Control Virus
AAV-344	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 4.

AAV5-LacZ Control Virus
AAV-345	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 5.

AAV6-LacZ Control Virus
AAV-346	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 6.

Bovine Lumpy skin disease virus (LSDV) control for western blot
LSDV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Rabies Virus Glycoprotein (~58 kda, RVG) control for western blot
RBVGP11-C	Alpha Diagnostics	100 ul	EUR 343.2

pGreenPuro Scramble Hairpin Control - Virus (for shRNAs and miRZips)
MZIP000-VA-1	SBI	>1 x 10^6 IFUs	EUR 652

scAAV1-GFP Control Virus
AAV-331	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 1.

scAAV2-GFP Control Virus
AAV-332	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 2.

scAAV3-GFP Control Virus
AAV-333	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 3.

scAAV4-GFP Control Virus
AAV-334	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 4.

scAAV5-GFP Control Virus
AAV-335	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 5.

scAAV6-GFP Control Virus
AAV-336	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 6.

Control/Blocking peptide for Tobacco Mosaic Virus Movement Protein
TMVMP11-P	Alpha Diagnostics	100 ug	EUR 196.8

Flow Control Fitting for Flypad
FLY1254	Scientific Laboratory Supplies	EACH	EUR 101.84

Control for ER, 4 cases (1.5mm)
ERC081	Pantomics	1	EUR 102
Description: IHC control array containing 4 breast cancer cases of strong, moderate, weak/nil estrogen receptor (ER) expressers in duplicates

Control for PR, 3 cases (1.5mm)
PRC061	Pantomics	1	EUR 102
Description: IHC control array containing 3 breast cancer cases of strong, moderate, low/negative progesterone receptor (PR) expressers in duplicates

Flow Control Fitting for Blowgun
FLY1252	Scientific Laboratory Supplies	EACH	EUR 80.95

Control for DOG1, 3 cases (1.5mm)
DOG1061	Pantomics	1	EUR 102
Description: IHC control array containing 3 GIST cases of strong, moderate, weak/nil DOG1 expressers in duplicates

Control for HER2, 4 cases (1.5mm)
HRC081	Pantomics	1	EUR 102
Description: IHC control array containing 4 breast cancer cases of strong, moderate, low and negative HER2 breast cancer expressers in duplicates

HSV-1 Virus Control Stock
20-4810020	Quidel	Single Use, 400 µL, shipped frozen	Ask for price
Description: Genetically Engineered BHK Cells

HSV-2 Virus Control Stock
20-4820020	Quidel	Single Use, 400 µL, shipped frozen	Ask for price
Description: Genetically Engineered BHK Cells

Deer IgG, semi-pure for ELISA (Control, non-immune, isotype control)
20024-2	Alpha Diagnostics	100 ug	EUR 270

NATtrol HIV Type 1 Strain: IIIB Linearity Panel (6 X 0.25 mL)
NATHIV1-LIN	Zeptometrix	6 X 0.25 mL	EUR 599

Control for Ckit, 6 samples (1.5mm)
CKIT061	Pantomics	1	EUR 102
Description: Gastrointestinal stroma tumors, 6 cores, 3 cases in duplicates showing strong, moderate and no expression of cKit molecule.

NATtrol BK Virus External Run Control, Low (6 X 1 mL)
NATBK-ERCL	Zeptometrix	6 X 1 mL	EUR 360

Eppendorf Centrifuge 5430R Knob Control Refrigerated- IVD Only
E5428000465	Scientific Laboratory Supplies	EACH	EUR 8115.6

NATtrol BK Virus External Run Control, Medium (6 X 1 mL)
NATBK-ERCM	Zeptometrix	6 X 1 mL	EUR 438

pRedTK-CMV Virus [positive control]
SR10052VA-1	SBI	>2 x 10^6 IFUs	EUR 625

Recombinant Zika Virus Envelop domain III (African) control for Western blot
ZEND21-C	Alpha Diagnostics	100 ul	EUR 343.2

pRedZeo-CMV Virus [positive control]
SR10046VA-1	SBI	>2 x 10^6 IFUs	EUR 625

SLLK, Control Peptide for TSP1 Inhibitor
HY-P0301	MedChemExpress	1mg	EUR 159.6

Bovine Viral Diarrhea Virus 1 (BVDV1) Erns Protein control for western blot
BVDR12-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Pseudorabies Virus glycoprotein B (PsRV gB) control for western blot
PSRVGB11-C	Alpha Diagnostics	100 ul	EUR 343.2

Control/Blocking peptide for Human WNT5a
WNT511-P	Alpha Diagnostics	100 ug	EUR 196.8

pGreenZeo-CMV Virus [positive control]
SR501VA-1	SBI	>2 x 10^6 IFUs	EUR 608

Recombinant (E. coli) Zika Virus NS1 Protein (African) control for Western blot
ZNS111-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant (HEK) Rift Valley Fever Virus NP protein control for Western blot
RVFNP12-C	Alpha Diagnostics	100 ul	EUR 343.2

Rec. Human CD21 protein control for WB
CD21-C	Alpha Diagnostics	100 ul	EUR 343.2

PAS/Glycogen, For Digestion (Control Slides)
TCS0024-100	ScyTek Laboratories	100 Slides	EUR 847.2

PAS/Glycogen, For Digestion (Control Slides)
TCS0024-25	ScyTek Laboratories	25 Slides	EUR 278.4

PAS/Glycogen, For Digestion (Control Slides)
TCS0024-5	ScyTek Laboratories	5 Slides	EUR 117.6

Rabies Virus Nucleoprotein (RV-NP) (~56 kda, RV-NP) control for western blot
RBVNP12-C	Alpha Diagnostics	100 ul	EUR 343.2

pGreenZeo-mCMV Virus [negative control]
SR500VA-1	SBI	>2 x 10^6 IFUs	EUR 608

Thiostatin Rat protein, control for western
TSTN11-C	Alpha Diagnostics	100 ul	EUR 343.2

Mouse IgG (-ve control for flow cytometry)
20008-1-100	Alpha Diagnostics	100 tests	EUR 123.6

Bovine Viral Diarrhea Virus 3 E2 (BVDV3-E2) Protein control for western blot
BVDE31-C	Alpha Diagnostics	100 ul	EUR 343.2

Rabbit IgG (-ve control for flow cytometry)
20009-1-100	Alpha Diagnostics	100 tests	EUR 123.6

NATtrol Cytomegalovirus (CMV) Strain: AD-169 Linearity Panel (6 X 0.25 mL)
NATCMV-LIN	Zeptometrix	6 X 0.25 mL	EUR 599

Recombinant African Swine fever virus (ASFV) P30 protein control for western blot
ASFV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant (E. coli) Zika Virus Envelop Protein (African) control for Western blot
ZENV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Pancreatic Amylase protein control for Western blot
PAMY13-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant Rat sialodacryoadenitis Virus (SDAV) nucleoprotein control for Western blot
SDAV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Control Sections for FD NeuroSilver™ Kit
PCS101	FD Neurotechnologies	each	EUR 69.6

Purified, Human S100 protein control for WB
S1002-C	Alpha Diagnostics	100 ul	EUR 343.2

Control/Blocking peptide for Human WNT-1
WNT111-P	Alpha Diagnostics	100 ug	EUR 548.4

Recombinant Polyoma Virus (KV, Pneumotropic virus) Capsid Protein 1 (VP1) control for Western blot
KVP14-C	Alpha Diagnostics	100 ul	EUR 343.2

Negative Control Antibody for Mouse Monoclonals
V8785-100UG	NSJ Bioreagents	100ug	EUR 349.3
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Negative Control Antibody for Mouse Monoclonals
V8785-20UG	NSJ Bioreagents	20ug	EUR 153.3
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Negative Control Antibody for Mouse Monoclonals
V8785SAF-100UG	NSJ Bioreagents	100ug	EUR 349.3
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Recombinant purified Mouse Pneumonia Virus (PVM) nucleoprotein control for Western blot
PVMNP14-C	Alpha Diagnostics	100 ul	EUR 343.2

SLLK, Control Peptide for TSP1 Inhibitor(TFA)
HY-P0301A	MedChemExpress	5mg	EUR 456

Purified, Bovine S100 protein control for WB
S1001-C	Alpha Diagnostics	100 ul	EUR 343.2

Positive Control for Anti-Rat MEH Antibody
MEHCON	Detroit R&D	100 uL	EUR 150

Recombinant (E. coli) Rift Valley Fever Virus Gn/G1 protein control for Western blot
RVFG11-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Apolipoprotein B protein control for WB
APOB21-C	Alpha Diagnostics	100 ul	EUR 343.2

Positive Control for Anti-Rat CYP2C Antibody
P2CCON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Rat CYP2D Antibody
P2DCON	Detroit R&D	100 uL	EUR 150

Recombinant (E.Coli) Japanese Encephalitis Virus (JEV) prM protein control for Western blot
JEV13-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant Classical Swine Fever Virus E2 protein (CSFV-E2) control for western blot
CSFE21-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant purified Rat Kilham Virus (KRV) capsid protein VP2 control for Western blot
KRVP21-C	Alpha Diagnostics	100 ul	EUR 343.2

Positive Control for Anti-Rat CYP2B1 Antibody
P2B1PTCON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Rat CYP3A2 Antibody
P3A2PTCON	Detroit R&D	100 uL	EUR 150

Haptoglobin Human Plasma protein control for WB
HGLB18-C	Alpha Diagnostics	100 ul	EUR 343.2

Control/Blocking peptide for Mouse Vimentin (Vim)
VIM11-C	Alpha Diagnostics	100 ug	EUR 196.8

Recombiant (E. Coli) Seneca valley Virus (SeV/SVV) VP1 protein control for Western blot
SEVC11-C	Alpha Diagnostics	100 ul	EUR 343.2

Mouse IgG Isotype control (purified) validated for
NG903	Innovex	7 ml	EUR 195
Description: Mouse IgG Isotype control (purified) validated for IHC; Ready-To-Use

Mouse IgG Isotype control (purified) validated for
NG903C	Innovex	1 ml	EUR 275
Description: Mouse IgG Isotype control (purified) validated for IHC; Concentrate; Minimum 1:50 dilution

Mouse IgM Isotype control (purified) validated for
NG906	Innovex	7 ml	EUR 265
Description: Mouse IgM Isotype control (purified) validated for IHC; Ready-To-Use

Mouse IgM Isotype control (purified) validated for
NG906C	Innovex	1 ml	EUR 295
Description: Mouse IgM Isotype control (purified) validated for IHC; Concentrate

Positive Control for Anti-Human CYP3A Antibody
P3ACON	Detroit R&D	100 uL	EUR 150

Recombinant purified Mouse Minute Virus (MVM) capsid protein VP2 control for Western blot
MVMVP21-C	Alpha Diagnostics	100 ul	EUR 343.2

Control/Blocking peptide for Ephrin-B2 antibody
NIVE2B-C	Alpha Diagnostics	100 ug	EUR 196.8

Positive Control for Anti-Human CYP1B1 Antibody
PH1B1CON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Human CYP2E1 Antibody
P2E1PTCON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Human CYP1A2 Antibody
P1A2CON	Detroit R&D	100 uL	EUR 150

Chicken Egg Ovalbumin protein control for Western
OVA11-C	Alpha Diagnostics	100 ul	EUR 343.2

Hendra Virus (Hev) glycoprotein (71-604 aa, >95%, his-tag) protein control for western blot
HEVG11-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant Tai Forest virus Glycoprotein (TAFV GP, Cote d'Ivoire-94) control for western blot
TVGP11-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant Zaire-Ebola virus nucleoprotein (Mayinga EBOV NP) protein control for Western
EVNP11-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant (sf9) Purified Sudan-Ebola virus glycoprotein protein control for Western Blot
SVGP21-C	Alpha Diagnostics	100 ul	Ask for price

Recombinant Lymphocytic choriomeningitis virus (LCMV) Nucleoprotein (NP) control for Western blot
LCMV14-C	Alpha Diagnostics	100 ul	EUR 343.2

Rat Ceruloplasmin protein control for western blot
CP17-C	Alpha Diagnostics	100 ul	EUR 343.2

Positive control tissue section for each individua
Control-slides-	Innovex	Set of 5	EUR 119
Description: Positive control tissue section for each individual antibody; Based on availability; INQUIRE

Positive control tissue section for each individua
Control-Slides-for-each-antibody	Innovex	Set of 25	EUR 355
Description: Positive control tissue section for each individual antibody; Based on availability; INQUIRE

Control sections for FD NeuroApop™ Kit (frozen)
PCS102-	FD Neurotechnologies	each	EUR 87.6

Control sections for FD NeuroApop™ Kit (frozen)
PCS102-2	FD Neurotechnologies	each	EUR 80.54
Description: Best quality products

Recombinant Classical Swine Fever Virus Erns protein (CSFV-Erns) control for western blot
CSFR11-C	Alpha Diagnostics	100 ul	EUR 343.2

Influenza A virus HA Control/blocking peptide
AB-23091-P	Alpha Diagnostics	100ug	EUR 196.8

Foot and mouth disease virus serotype O, 3D (FMDO-3D) protein control for western blot
FMDO3D11-C	Alpha Diagnostics	100 ul	EUR 416.4

Mouse Ceruloplasmin protein control for western blot
CP16-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Flagellin (salmonella) protein control for WB
FLGN17-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Hemopexin purified protein control for Western
HPEX11-C	Alpha Diagnostics	100 ul	EUR 343.2

Hemopexin Mouse, purified protein control for Western
HPEX16-C	Alpha Diagnostics	100 ul	EUR 343.2

Q-VE-OPh (Negative Control for Q-VD-OPh)
GW8990-1	Glentham Life Sciences	1	EUR 228.1

Human Apolipoprotein C-I protein control for WB
APOC11-C	Alpha Diagnostics	100 ul	EUR 343.2

Control sections for FD NeuroApop™ Kit (paraffin)
PCS102-1	FD Neurotechnologies	each	EUR 80.44
Description: Best quality products

Purified Human Survivin protein for WB +ve control
SURV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant (E. coli) Rift Valley Fever Virus polymerase L protein control for Western blot
RVFL11-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Apolipoprotein C-II protein control for WB
APOC22-C	Alpha Diagnostics	100 ul	EUR 343.2

Monkey (Rhesus) Serum Albumin protein control for WB
ALBMK21-C	Alpha Diagnostics	100 ul	EUR 343.2

Monkey (Rhesus) Serum Albumin protein control for WB
ALBMK22-C	Alpha Diagnostics	100 ul	EUR 343.2

Positive Control for Anti-Rat CHP2B1/2 Antibody
P2B12PTCON	Detroit R&D	100 uL	EUR 150

Bovine Adenosine deaminase protein control for Western
ADA11-C	Alpha Diagnostics	100 ul	EUR 343.2

Positive Control for anti-GST p-forms: rat P
GSTCON3	Detroit R&D	100 uL	EUR 150

Virus-Like Particle (VLP) Protein Isotype Control
VLP-N5213	ACROBIOSYSTEMS	30ug	EUR 428
Description: VLP isotype control (VLP-N5213) is expressed from human 293 cells (HEK293).

Recombinant (E.coli) Respiratory Syncytial Virus fusion (RSV-F) protein control for western blot
RSV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Apolipoprotein C-III protein control for WB
APOC32-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified human Catalase (CATL) protein control for WB
CATL11-C	Alpha Diagnostics	100 ul	EUR 343.2

Positive Control for Anti-Rat CYP1A1/1A2 Antibody
P1ACON	Detroit R&D	100 uL	EUR 150

Purified bovine Lactoferrin protein control for Western
LTF13-C	Alpha Diagnostics	100 ul	EUR 343.2

NATtrol Zika Virus, External Run Control, Low (6 x 1 mL)
NATZIKV-ERCL	Zeptometrix	6 x 1 mL	EUR 350

Chicken Egg white proteins total control for Western
CEGW12-C	Alpha Diagnostics	100 ul	EUR 343.2

Rabbit Beta Actin (muscle) protein control for Western
ACTB15-C	Alpha Diagnostics	100 ul	EUR 388.8

Recombinant Poliomyelitis Virus 1 Viral Protein 1 (Sabin; POLV1-VP1) control for Western blot
POLV15-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Native Retinol binding protein (RBP) control for Western
RBP41-C	Alpha Diagnostics	100 ul	EUR 343.2

Human plasma Apolipoprotein E protein control for WB
APOE13-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Plasma Apolipoprotein J protein control for WB
APOJ13-C	Alpha Diagnostics	100 ul	EUR 343.2

Chicken Egg yellow proteins total control for Western
CEYP12-C	Alpha Diagnostics	100 ul	EUR 343.2

GC Control
A23	DataApex	-	EUR 600
Description: SW module for GC control

LC Control
A24	DataApex	-	EUR 600
Description: SW module for HPLC/CE control (pump, det, etc.)

AS Control
A26	DataApex	-	EUR 330
Description: SW module for AS control

Recombinant purified Human Papilloma Virus 6 (HPV6) late protein L1 (full length) control for WB
HPV06L11-C	Alpha Diagnostics	100 ul	EUR 343.2

Lectin binding native protein (positive control for SNA lectin)
LBP16-N-1	Alpha Diagnostics	1 ml	EUR 270

Chicken Serum Albumin protein control for Western blot
ALBC15-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Salivary Amylase protein positive control for WB
SAMY16-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified, recombinant Human TACE control protein for WB
TACE11-C	Alpha Diagnostics	100 ul	EUR 343.2

Lectin binding native protein (negative control for all lectins)
LNP15-N-1	Alpha Diagnostics	1 ml	EUR 270

Vaccinia virus Complement control protein C3 (VACWR025)
1-CSB-YP302389VAI	Cusabio	EUR 814.80 EUR 402.00 EUR 2606.40 EUR 1261.20 EUR 1730.40 EUR 522.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Vaccinia virus Complement control protein C3(VACWR025) expressed in Yeast

Mouse Angiopoietin 3 (Ang-3) protein control for WB
ANG31-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Angiopoietin 4 (Ang-4) protein control for WB
ANG41-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Rat C-Reactive Protein (CRP) control for WB
CRP16-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Dog C-Reactive Protein (CRP) control for WB
CRP18-C	Alpha Diagnostics	100 ul	EUR 343.2

Results: We identified four network modules with statistical significance (P <0.05), two of which are connected to the PASI score, while the other two are connected to the 8-week treatment and ΔPASI. In patients with psoriasis, inflammatory pathway and inhibit activated G-protein signaling genes (GTPase IMAP family members and the G protein-coupled receptors) co-occur, including high expression of CD83 and CD69 and low expression of CD160 and CD180, compared to healthy controls.

Accompanying LJD treatment and remission of lesions, the expression of CD69 and associated cell cycle genes including CCNA2, CCNB2, Cdk1, and TOP2A down-regulated. LJD inhibitory role on CD69 expression was confirmed by activating naive CD4 + T lymphocytes

Conclusions: Our study suggests that psoriasis is marked with immune status is not balanced with dendritic cell activation and inflammation associated lymphocytes as well as NK-cells and B cell-related defense response aberrance. LJD play a role in the inhibition of T cell activation, a process which is located downstream of the pathological cascade of psoriasis.