Epidemiology and Diagnosis of Mucormycosis: An Update

Mucormycosis is a fungal infection angioinvasive, because fungi of the Mucorales order. incidents that can not be measured precisely, because there are few population-based studies, but some studies have shown that it increases. Mucormycosis prevalence in India is approximately 80 times the prevalence in developed countries, to about 0.14 cases per 1000 population. Diabetes mellitus is a major underlying disease globally, especially in low- and middle-countries. In developed countries the underlying disease is the most common hematologic malignancy and transplantation.

Τhe mucormycosis epidemiology evolved as a new immunomodulatory agent used in the treatment of cancer and autoimmune diseases, and as a modern diagnostic tools lead to earlier identification of rare genera / species like Apophysomyces or Saksenaea complex. Additionally, new risk factors reported from Asia, including post-pulmonary tuberculosis and chronic kidney disease. New species arise including Rhizopus homothallicus, Thamnostylum lucknowense, irregularis Mucor and Saksenaea erythrospora. Diagnosis remains of mucormycosis challenging. Clinical approach to diagnosis has a sensitivity and low specificity, but helps in increasing suspicion and encourage initiation of laboratory testing.

Histopathology, direct examination and culture remain important tools, although improved molecular methods. Internal transcribed spacer region (ITS) is the most widely sequencing of DNA regions of the fungus and is recommended as first-line method for the identification of the species Mucorales. new molecular platform that is being investigated and new genetic targets mushrooms are being explored. molecular-based methods have gained acceptance to confirm infection when applied to the network. Mucorales detection method on the DNA in the blood have shown promising results for the early diagnosis and quick and can be used as a screening test in high-risk patients, but it has been validated in clinical studies. More, much needed, fast method that does not require invasive procedures, such as breath test metabolomics-based point-of-care, or based on serology, are being developed and hopefully will be evaluated in the near future.

Clinical analysis of network-connected nature expresses markers of psoriasis treatment of active transcription with Liangxue-Jiedu decoction

Ethnopharmacological relevance: Psoriasis is a recurrent inflammatory skin disease complex with different pathological changes in various stages. Psoriasis in the active phase, which is comparable to the kind of blood-heat in traditional Chinese medicine (TCM), has been conventionally treated by Liangxue Jiedu decoction (LJD) in TCM for decades with proven success. According to TCM theory, LJD has the function of removing heat and pathogenic factors from the blood.

The purpose of this research: We aimed to determine the molecular features associated with blood-heat syndrome active psoriasis and to identify genes respond to treatment LJD accompanied by a lesion remission.
Materials and methods: healthy volunteers and patients with psoriasis who meet the diagnostic criteria specifically recruited. Twenty-six profiled transcriptome of cells of peripheral blood mononuclear (PBMC) from 10 patients with psoriasis (pre- and post-treatment) and 6 healthy volunteers.

Data sequencing RNA is analyzed using an integrated approach which combines differential analysis of gene expression (DGEA) and network analysis of gene co-expression of weighted (WGCNA), where the expression of genes associated with some clinical characteristics, including the psoriasis and severity index (PASI), and the increased rate of skin lesions (ΔPASI). LJD action then verified using in vitro cell assay combined flow cytometric analysis and RT-PCR.

NATtrol GBS Negative Control (6 X 0.5 mL)
NATLAC-6MC-IVD	Zeptometrix	6 X 0.5 mL	EUR 301

NATtrol MRSA Positive Control (6 X 0.5 mL)
NATMRSA-6MC-IVD	Zeptometrix	6 X 0.5 mL	EUR 292

NATtrol SA Positive Control (6 X 0.5 mL)
NATMSSA-6MC-IVD	Zeptometrix	6 X 0.5 mL	EUR 292

NATtrol Norovirus Negative Control (6 X 0.5 mL)
NATROTA-6MC-IVD	Zeptometrix	6 X 0.5 mL	EUR 195

NATtrol RSV Positive Control (6 X 0.5 mL)
NATRSV-6C-IVD	Zeptometrix	6 X 0.5 mL	EUR 216

NATtrol GBS Positive Control (6 x 0.5 mL)
NATSAG-6MC-IVD	Zeptometrix	6 x 0.5 mL	EUR 301

Eppendorf Centrifuge 5430R Knob Control Refrigerated- IVD Only
E5428000465	Scientific Laboratory Supplies	EACH	EUR 7164.9

NATtrol Clostridium difficile Positive Control (6 X 0.5 mL)
NATCDI-6MC-IVD	Zeptometrix	6 X 0.5 mL	EUR 301

NATtrol Clostridium difficile Negative Control (6 X 0.5 mL)
NATCSO-6MC-IVD	Zeptometrix	6 X 0.5 mL	EUR 301

NATtrol Influenza/RSV Negative Control (6 X 0.5 mL)
NATCXVA9-6C-IVD	Zeptometrix	6 X 0.5 mL	EUR 201

NATtrol MRSA/SA Negative Control (6 X 0.5 mL)
NATMSSE-6MC-IVD	Zeptometrix	6 X 0.5 mL	EUR 292

NATtrol Influenza A/B Positive Control (6 X 0.5 mL)
NATFLUAB-6C-IVD	Zeptometrix	6 X 0.5 mL	EUR 201

NATtrol Neisseria gonorrhoeae Positive Control Pack (6 X 1.25 mL)
NATNG-6MC-IVD	Zeptometrix	6 X 1.25 mL	EUR 354

NATtrol Norovirus GI/GII Positive Control (6 X 0.5 mL)
NATNOV-6MC-IVD	Zeptometrix	6 X 0.5 mL	EUR 195

Goat IgG (-ve control for flow cytometry) (isotype control)
20011-100	Alpha Diagnostics	100 test	EUR 123.6

BSA Control for AGE-BSA
35R-AA007	Fitzgerald	10 mg	EUR 268.8
Description: BSA Control for AGE protein (BSA modified), Cat No. 30R-AA007

Flow Control Fitting for Blowgun
FLY1252	Scientific Laboratory Supplies	EACH	EUR 53.92

Flow Control Fitting for Flypad
FLY1254	Scientific Laboratory Supplies	EACH	EUR 67.26

BSA Control for Age-BSA
2221-BSA	Biovision	each	EUR 210

Purified Nipah virus Glycoprotein control for Western Blotting
NIV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Nipah virus Nucleoprotein control for Western Blotting
NIV21-C	Alpha Diagnostics	100 ul	EUR 270

Camelpox virus H3L/p35 protein control for western blot
CPOX11-C	Alpha Diagnostics	100 ul	EUR 343.2

Mayaro virus (MAYV) Capsid Protein control for Western Blotting
MAYV31-C	Alpha Diagnostics	100 ul	EUR 343.2

Mayaro virus (MAYV) nsP1 protein control for Western Blotting
MAYV41-C	Alpha Diagnostics	100 ul	EUR 343.2

Mayaro virus (MAYV) 6K Protein control for Western Blotting
MAYV51-C	Alpha Diagnostics	100 ug	EUR 343.2

Mayaro virus (MAYV) E3 protein control for Western Blotting
MAYV61-C	Alpha Diagnostics	100 ul	EUR 343.2

pGreenPuro Scramble Hairpin Control - Virus (for shRNAs and miRZips)
MZIP000-VA-1	SBI	>1 x 10^6 IFUs	EUR 859.2

Control/Blocking peptide for Tobacco Mosaic Virus Movement Protein
TMVMP11-P	Alpha Diagnostics	100 ug	EUR 196.8

Zika Virus prM Protein (African) control for Western blot
ZPRM11-C	Alpha Diagnostics	100 ul	EUR 343.2

Control for Ckit, 6 samples (1.5mm)
CKIT061	Pantomics	1	EUR 102
Description: Gastrointestinal stroma tumors, 6 cores, 3 cases in duplicates showing strong, moderate and no expression of cKit molecule.

Control for DOG1, 3 cases (1.5mm)
DOG1061	Pantomics	1	EUR 102
Description: IHC control array containing 3 GIST cases of strong, moderate, weak/nil DOG1 expressers in duplicates

Control for ER, 4 cases (1.5mm)
ERC081	Pantomics	1	EUR 102
Description: IHC control array containing 4 breast cancer cases of strong, moderate, weak/nil estrogen receptor (ER) expressers in duplicates

Control for HER2, 4 cases (1.5mm)
HRC081	Pantomics	1	EUR 102
Description: IHC control array containing 4 breast cancer cases of strong, moderate, low and negative HER2 breast cancer expressers in duplicates

SLLK, Control Peptide for TSP1 Inhibitor
HY-P0301	MedChemExpress	1mg	EUR 159.6

Control for PR, 3 cases (1.5mm)
PRC061	Pantomics	1	EUR 102
Description: IHC control array containing 3 breast cancer cases of strong, moderate, low/negative progesterone receptor (PR) expressers in duplicates

PAS/Glycogen, For Digestion (Control Slides)
TCS0024-100	ScyTek Laboratories	100 Slides	EUR 847.2

PAS/Glycogen, For Digestion (Control Slides)
TCS0024-25	ScyTek Laboratories	25 Slides	EUR 278.4

PAS/Glycogen, For Digestion (Control Slides)
TCS0024-5	ScyTek Laboratories	5 Slides	EUR 117.6

Thiostatin Rat protein, control for western
TSTN11-C	Alpha Diagnostics	100 ul	EUR 343.2

Control/Blocking peptide for Human WNT5a
WNT511-P	Alpha Diagnostics	100 ug	EUR 196.8

Negative Control Antibody for Mouse Monoclonals
V8785-100UG	NSJ Bioreagents	100ug	EUR 499
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Negative Control Antibody for Mouse Monoclonals
V8785-20UG	NSJ Bioreagents	20ug	EUR 219
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Negative Control Antibody for Mouse Monoclonals
V8785SAF-100UG	NSJ Bioreagents	100ug	EUR 499
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Eppendorf Centrifuge 5425R Keypad Control With Rotor Refrigerated EU-IVD
E5406000062	Scientific Laboratory Supplies	EACH	EUR 5434.38

Eppendorf Centrifuge 5425R Keypad Control Without Rotor Refrigerated EU-IVD
E5406000267	Scientific Laboratory Supplies	EACH	EUR 5055.9

Eppendorf Centrifuge 5425R Knob Control With Rotor Refrigerated EU-IVD
E5406000461	Scientific Laboratory Supplies	EACH	EUR 5434.38

Eppendorf Centrifuge 5425R Knob Control Without Rotor Refrigerated EU-IVD
E5406000666	Scientific Laboratory Supplies	EACH	EUR 5055.9

Deer IgG, semi-pure for ELISA (Control, non-immune, isotype control)
20024-2	Alpha Diagnostics	100 ug	EUR 270

NATtrol Chlamydia trachomatis Positive Control Pack (6 X 1.25 mL)
NATCT(434)-6MC-IVD	Zeptometrix	6 X 1.25 mL	EUR 354

NATtrol CT/NG Negative Control Pack (6 X 1.25 mL)
NATCT/NGNEG-6MC-IVD	Zeptometrix	6 X 1.25 mL	EUR 219

AAV1-GFP Control Virus
AAV-301	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 1.

AAV2-GFP Control Virus
AAV-302	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 2.

AAV3-GFP Control Virus
AAV-303	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 3.

AAV4-GFP Control Virus
AAV-304	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 4.

AAV5-GFP Control Virus
AAV-305	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 5.

AAV6-GFP Control Virus
AAV-306	Cell Biolabs	50 ?L	EUR 1221.6
Description: GFP control virus of AAV serotype 6.

AAV2-Cre Control Virus
AAV-310	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 2.

AAV1-Cre Control Virus
AAV-311	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 1.

AAV3-Cre Control Virus
AAV-313	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 3.

AAV4-Cre Control Virus
AAV-314	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 4.

AAV5-Cre Control Virus
AAV-315	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 5.

AAV6-Cre Control Virus
AAV-316	Cell Biolabs	50 ?L	EUR 1221.6
Description: Cre control virus of AAV serotype 6.

AAV2-Luc Control Virus
AAV-320	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 2.

AAV1-Luc Control Virus
AAV-321	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 1.

AAV3-Luc Control Virus
AAV-323	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 3.

AAV4-Luc Control Virus
AAV-324	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 4.

AAV5-Luc Control Virus
AAV-325	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 5.

AAV6-Luc Control Virus
AAV-326	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 6.

scAAV1-GFP Control Virus
AAV-331	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 1.

scAAV2-GFP Control Virus
AAV-332	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 2.

scAAV3-GFP Control Virus
AAV-333	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 3.

scAAV4-GFP Control Virus
AAV-334	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 4.

scAAV5-GFP Control Virus
AAV-335	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 5.

scAAV6-GFP Control Virus
AAV-336	Cell Biolabs	50 ?L	EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 6.

AAV1-LacZ Control Virus
AAV-341	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 1.

AAV2-LacZ Control Virus
AAV-342	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 2.

AAV3-LacZ Control Virus
AAV-343	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 3.

AAV4-LacZ Control Virus
AAV-344	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 4.

AAV5-LacZ Control Virus
AAV-345	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 5.

AAV6-LacZ Control Virus
AAV-346	Cell Biolabs	50 ?L	EUR 1221.6
Description: LacZ control virus of AAV serotype 6.

AAV1 Null Control Virus
AAV-351	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 1.

AAV2 Null Control Virus
AAV-352	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 2.

AAV3 Null Control Virus
AAV-353	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 3.

AAV4 Null Control Virus
AAV-354	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 4.

AAV5 Null Control Virus
AAV-355	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 5.

AAV6 Null Control Virus
AAV-356	Cell Biolabs	50 ?L	EUR 1221.6
Description: Null (empty) control virus of AAV serotype 6.

Holder for Plasmid Midi, Maxi and Maxi plus, Ion Exchange column
FAPDE-holder-for-ion-exchange	Favorgen	1 prep	EUR 189.6

Bovine Lumpy skin disease virus (LSDV) control for western blot
LSDV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant Rat sialodacryoadenitis Virus (SDAV) nucleoprotein control for Western blot
SDAV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Rabies Virus Glycoprotein (~58 kda, RVG) control for western blot
RBVGP11-C	Alpha Diagnostics	100 ul	EUR 343.2

Mouse IgG (-ve control for flow cytometry)
20008-1-100	Alpha Diagnostics	100 tests	EUR 123.6

Rabbit IgG (-ve control for flow cytometry)
20009-1-100	Alpha Diagnostics	100 tests	EUR 123.6

Human Apolipoprotein B protein control for WB
APOB21-C	Alpha Diagnostics	100 ul	EUR 343.2

Rec. Human CD21 protein control for WB
CD21-C	Alpha Diagnostics	100 ul	EUR 343.2

Mouse Ceruloplasmin protein control for western blot
CP16-C	Alpha Diagnostics	100 ul	EUR 343.2

Rat Ceruloplasmin protein control for western blot
CP17-C	Alpha Diagnostics	100 ul	EUR 343.2

Bovine Adenosine deaminase protein control for Western
ADA11-C	Alpha Diagnostics	100 ul	EUR 343.2

Chicken Egg Ovalbumin protein control for Western
OVA11-C	Alpha Diagnostics	100 ul	EUR 343.2

Mouse negative control sera (purified) for IHC
NCM802M	Innovex	7 ml	EUR 238.8

Control/Blocking peptide for Ephrin-B2 antibody
NIVE2B-C	Alpha Diagnostics	100 ug	EUR 196.8

Positive Control for Anti-Rat MEH Antibody
MEHCON	Detroit R&D	100 uL	EUR 150

Purified bovine Lactoferrin protein control for Western
LTF13-C	Alpha Diagnostics	100 ul	EUR 343.2

Haptoglobin Human Plasma protein control for WB
HGLB18-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Hemopexin purified protein control for Western
HPEX11-C	Alpha Diagnostics	100 ul	EUR 343.2

Hemopexin Mouse, purified protein control for Western
HPEX16-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Flagellin (salmonella) protein control for WB
FLGN17-C	Alpha Diagnostics	100 ul	EUR 343.2

SLLK, Control Peptide for TSP1 Inhibitor(TFA)
HY-P0301A	MedChemExpress	5mg	EUR 456

Positive Control for Anti-Human CYP1A2 Antibody
P1A2CON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Rat CYP2B1 Antibody
P2B1PTCON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Rat CYP2C Antibody
P2CCON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Rat CYP2D Antibody
P2DCON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Human CYP2E1 Antibody
P2E1PTCON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Rat CYP3A2 Antibody
P3A2PTCON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Human CYP3A Antibody
P3ACON	Detroit R&D	100 uL	EUR 150

Control Sections for FD NeuroSilver™ Kit
PCS101	FD Neurotechnologies	each	EUR 69.6

Positive Control for Anti-Human CYP1B1 Antibody
PH1B1CON	Detroit R&D	100 uL	EUR 150

Purified, Bovine S100 protein control for WB
S1001-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified, Human S100 protein control for WB
S1002-C	Alpha Diagnostics	100 ul	EUR 343.2

Control/Blocking peptide for Mouse Vimentin (Vim)
VIM11-C	Alpha Diagnostics	100 ug	EUR 196.8

Control/Blocking peptide for Human WNT-1
WNT111-P	Alpha Diagnostics	100 ug	EUR 548.4

Control siRNA Vector (pGB-control)
9500C-20	Biovision	each	EUR 405.6

Recombinant Lymphocytic choriomeningitis virus (LCMV) Nucleoprotein (NP) control for Western blot
LCMV14-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Pseudorabies Virus glycoprotein B (PsRV gB) control for western blot
PSRVGB11-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant Zika Virus Envelop domain III (African) control for Western blot
ZEND21-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant purified Mouse Pneumonia Virus (PVM) nucleoprotein control for Western blot
PVMNP14-C	Alpha Diagnostics	100 ul	EUR 343.2

pRedZeo-CMV Virus [positive control]
SR10046VA-1	SBI	>2 x 10^6 IFUs	EUR 826.8

pRedTK-CMV Virus [positive control]
SR10052VA-1	SBI	>2 x 10^6 IFUs	EUR 826.8

pGreenZeo-mCMV Virus [negative control]
SR500VA-1	SBI	>2 x 10^6 IFUs	EUR 806.4

pGreenZeo-CMV Virus [positive control]
SR501VA-1	SBI	>2 x 10^6 IFUs	EUR 806.4

Human Apolipoprotein C-I protein control for WB
APOC11-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Apolipoprotein C-II protein control for WB
APOC22-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Apolipoprotein C-III protein control for WB
APOC32-C	Alpha Diagnostics	100 ul	EUR 343.2

Human plasma Apolipoprotein E protein control for WB
APOE13-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Plasma Apolipoprotein J protein control for WB
APOJ13-C	Alpha Diagnostics	100 ul	EUR 343.2

Chicken Serum Albumin protein control for Western blot
ALBC15-C	Alpha Diagnostics	100 ul	EUR 343.2

Monkey (Rhesus) Serum Albumin protein control for WB
ALBMK21-C	Alpha Diagnostics	100 ul	EUR 343.2

Monkey (Rhesus) Serum Albumin protein control for WB
ALBMK22-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant Beta Lactamase protein control for Western blot
BLAC11-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified human Catalase (CATL) protein control for WB
CATL11-C	Alpha Diagnostics	100 ul	EUR 343.2

Positive Control for Anti-Human Cytochrome b5 Antibody
Cb5CON	Detroit R&D	100 uL	EUR 150

Chicken Egg yellow proteins total control for Western
CEYP12-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Cholera Toxin protein control for Western Blot
CTOX11-C	Alpha Diagnostics	100 ul	EUR 343.2

Chicken Egg Conalbumin (ovotransferrin) protein control for Western
CECA15-C	Alpha Diagnostics	100 ul	EUR 343.2

Chicken Egg white proteins total control for Western
CEGW12-C	Alpha Diagnostics	100 ul	EUR 343.2

Chicken Ovomucoid (trypsin inhibitor) protein control for Western
COVM13-C	Alpha Diagnostics	100 ul	EUR 343.2

Rabbit Beta Actin (muscle) protein control for Western
ACTB15-C	Alpha Diagnostics	100 ul	EUR 388.8

Myoglobin, Human Cardiac, purified protein control for western
MYG17-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Lassa fever Nucleoprotein control for Western Blotting
LFNP15-C-10	Alpha Diagnostics	100 ul	EUR 343.2

Control/Blocking peptide for Mouse Histone deacetylase 1
HDAC111-P	Alpha Diagnostics	100 ug	EUR 196.8

Purified Human Neutrophil Elastase protein control for WB
ESTE11-C	Alpha Diagnostics	100 ul	EUR 343.2

Positive Control for Anti-Rat CYP1A1/1A2 Antibody
P1ACON	Detroit R&D	100 uL	EUR 150

Positive Control for Anti-Rat CHP2B1/2 Antibody
P2B12PTCON	Detroit R&D	100 uL	EUR 150

Human Prothrombin (Factor II) protein control for Western
PRTN11-C	Alpha Diagnostics	100 ul	EUR 343.2

Mouse Prothrombin (Factor II) protein control for Western
PRTN13-C	Alpha Diagnostics	100 ul	EUR 343.2

Control sections for FD NeuroApop™ Kit (frozen)
PCS102-	FD Neurotechnologies	each	EUR 87.6

Control sections for FD NeuroApop™ Kit (paraffin)
PCS102-1	FD Neurotechnologies	each	EUR 80.44
Description: Best quality products

Control sections for FD NeuroApop™ Kit (frozen)
PCS102-2	FD Neurotechnologies	each	EUR 80.54
Description: Best quality products

Human Pancreatic Amylase protein control for Western blot
PAMY13-C	Alpha Diagnostics	100 ul	EUR 343.2

Human Salivary Amylase protein positive control for WB
SAMY16-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified, recombinant Human TACE control protein for WB
TACE11-C	Alpha Diagnostics	100 ul	EUR 343.2

Purified Human Survivin protein for WB +ve control
SURV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Quality Control
abx098966-1vial	Abbexa	1 vial	EUR 360

pMD18- Control
PVT10563	Lifescience Market	2 ug	EUR 319.2

pMD19- Control
PVT10564	Lifescience Market	2 ug	EUR 319.2

Recombinant African Swine fever virus (ASFV) P30 protein control for western blot
ASFV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Bovine Viral Diarrhea Virus 1 (BVDV1) Erns Protein control for western blot
BVDR12-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant Zaire-Ebola virus nucleoprotein (Mayinga EBOV NP) protein control for Western
EVNP11-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant (E.Coli) Japanese Encephalitis Virus (JEV) prM protein control for Western blot
JEV13-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant (HEK) Rift Valley Fever Virus NP protein control for Western blot
RVFNP12-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant (sf9) Purified Sudan-Ebola virus glycoprotein protein control for Western Blot
SVGP21-C	Alpha Diagnostics	100 ul	Ask for price

Recombinant (E. coli) Zika Virus Envelop Protein (African) control for Western blot
ZENV11-C	Alpha Diagnostics	100 ul	EUR 343.2

Recombinant (E. coli) Zika Virus NS1 Protein (African) control for Western blot
ZNS111-C	Alpha Diagnostics	100 ul	EUR 343.2

Ivd/ Rat Ivd ELISA Kit
ELI-39421r	Lifescience Market	96 Tests	EUR 1063.2

Recombinant Polyoma Virus (KV, Pneumotropic virus) Capsid Protein 1 (VP1) control for Western blot
KVP14-C	Alpha Diagnostics	100 ul	EUR 343.2

NATtrol BK Virus External Run Control, Low (6 X 1 mL)
NATBK-ERCL	Zeptometrix	6 X 1 mL	EUR 406.94
Description: Please contact Gentaur in order to receive the datasheet of the product.

NATtrol BK Virus External Run Control, Medium (6 X 1 mL)
NATBK-ERCM	Zeptometrix	6 X 1 mL	EUR 481.82
Description: Please contact Gentaur in order to receive the datasheet of the product.

Rat neurofascin (Nfasc)-control Control/blocking peptide
AB-23249-CP	Alpha Diagnostics	100ug	EUR 196.8

Alpha 2-Macroglobulin (A2M), Human protein control for WB
A2MG11-C	Alpha Diagnostics	100 ul	EUR 343.2

Alpha-1-Acid Glycoprotein Protein, Dog, control for western
A1AG17-C	Alpha Diagnostics	100 ul	EUR 343.2

Alpha-1-Acid Glycoprotein Protein, Mouse, control for western
A1AG18-C	Alpha Diagnostics	100 ul	EUR 343.2

Results: We identified four network modules with statistical significance (P <0.05), two of which are connected to the PASI score, while the other two are connected to the 8-week treatment and ΔPASI. In patients with psoriasis, inflammatory pathway and inhibit activated G-protein signaling genes (GTPase IMAP family members and the G protein-coupled receptors) co-occur, including high expression of CD83 and CD69 and low expression of CD160 and CD180, compared to healthy controls.

Accompanying LJD treatment and remission of lesions, the expression of CD69 and associated cell cycle genes including CCNA2, CCNB2, Cdk1, and TOP2A down-regulated. LJD inhibitory role on CD69 expression was confirmed by activating naive CD4 + T lymphocytes

Conclusions: Our study suggests that psoriasis is marked with immune status is not balanced with dendritic cell activation and inflammation associated lymphocytes as well as NK-cells and B cell-related defense response aberrance. LJD play a role in the inhibition of T cell activation, a process which is located downstream of the pathological cascade of psoriasis.