Epidemiology and Diagnosis of Mucormycosis: An Update

Mucormycosis is a fungal infection angioinvasive, because fungi of the Mucorales order. incidents that can not be measured precisely, because there are few population-based studies, but some studies have shown that it increases. Mucormycosis prevalence in India is approximately 80 times the prevalence in developed countries, to about 0.14 cases per 1000 population. Diabetes mellitus is a major underlying disease globally, especially in low- and middle-countries. In developed countries the underlying disease is the most common hematologic malignancy and transplantation.

Τhe mucormycosis epidemiology evolved as a new immunomodulatory agent used in the treatment of cancer and autoimmune diseases, and as a modern diagnostic tools lead to earlier identification of rare genera / species like Apophysomyces or Saksenaea complex. Additionally, new risk factors reported from Asia, including post-pulmonary tuberculosis and chronic kidney disease. New species arise including Rhizopus homothallicus, Thamnostylum lucknowense, irregularis Mucor and Saksenaea erythrospora. Diagnosis remains of mucormycosis challenging. Clinical approach to diagnosis has a sensitivity and low specificity, but helps in increasing suspicion and encourage initiation of laboratory testing.

Histopathology, direct examination and culture remain important tools, although improved molecular methods. Internal transcribed spacer region (ITS) is the most widely sequencing of DNA regions of the fungus and is recommended as first-line method for the identification of the species Mucorales. new molecular platform that is being investigated and new genetic targets mushrooms are being explored. molecular-based methods have gained acceptance to confirm infection when applied to the network. Mucorales detection method on the DNA in the blood have shown promising results for the early diagnosis and quick and can be used as a screening test in high-risk patients, but it has been validated in clinical studies. More, much needed, fast method that does not require invasive procedures, such as breath test metabolomics-based point-of-care, or based on serology, are being developed and hopefully will be evaluated in the near future.

 Epidemiology and Diagnosis of Mucormycosis: An Update
Epidemiology and Diagnosis of Mucormycosis: An Update

Clinical analysis of network-connected nature expresses markers of psoriasis treatment of active transcription with Liangxue-Jiedu decoction

Ethnopharmacological relevance: Psoriasis is a recurrent inflammatory skin disease complex with different pathological changes in various stages. Psoriasis in the active phase, which is comparable to the kind of blood-heat in traditional Chinese medicine (TCM), has been conventionally treated by Liangxue Jiedu decoction (LJD) in TCM for decades with proven success. According to TCM theory, LJD has the function of removing heat and pathogenic factors from the blood.

The purpose of this research: We aimed to determine the molecular features associated with blood-heat syndrome active psoriasis and to identify genes respond to treatment LJD accompanied by a lesion remission.
Materials and methods: healthy volunteers and patients with psoriasis who meet the diagnostic criteria specifically recruited. Twenty-six profiled transcriptome of cells of peripheral blood mononuclear (PBMC) from 10 patients with psoriasis (pre- and post-treatment) and 6 healthy volunteers.

Data sequencing RNA is analyzed using an integrated approach which combines differential analysis of gene expression (DGEA) and network analysis of gene co-expression of weighted (WGCNA), where the expression of genes associated with some clinical characteristics, including the psoriasis and severity index (PASI), and the increased rate of skin lesions (ΔPASI). LJD action then verified using in vitro cell assay combined flow cytometric analysis and RT-PCR.

BSA Control for AGE-BSA

35R-AA007 10 mg
EUR 268.8
Description: BSA Control for AGE protein (BSA modified), Cat No. 30R-AA007

BSA Control for Age-BSA

2221-BSA
EUR 210

Flow Control Fitting for Blowgun

FLY1252 EACH
EUR 53.92

Flow Control Fitting for Flypad

FLY1254 EACH
EUR 67.26

Purified Nipah virus Glycoprotein control for Western Blotting

NIV11-C 100 ul
EUR 343.2

Purified Nipah virus Nucleoprotein control for Western Blotting

NIV21-C 100 ul
EUR 270

Camelpox virus H3L/p35 protein control for western blot

CPOX11-C 100 ul
EUR 343.2

Mayaro virus (MAYV) Capsid Protein control for Western Blotting

MAYV31-C 100 ul
EUR 343.2

Mayaro virus (MAYV) nsP1 protein control for Western Blotting

MAYV41-C 100 ul
EUR 343.2

Mayaro virus (MAYV) 6K Protein control for Western Blotting

MAYV51-C 100 ug
EUR 343.2

Mayaro virus (MAYV) E3 protein control for Western Blotting

MAYV61-C 100 ul
EUR 343.2

pGreenPuro Scramble Hairpin Control - Virus (for shRNAs and miRZips)

MZIP000-VA-1 >1 x 10^6 IFUs
EUR 859.2

Control/Blocking peptide for Tobacco Mosaic Virus Movement Protein

TMVMP11-P 100 ug
EUR 196.8

Zika Virus prM Protein (African) control for Western blot

ZPRM11-C 100 ul
EUR 343.2

Control for Ckit, 6 samples (1.5mm)

CKIT061 1
EUR 102
Description: Gastrointestinal stroma tumors, 6 cores, 3 cases in duplicates showing strong, moderate and no expression of cKit molecule.

Control for DOG1, 3 cases (1.5mm)

DOG1061 1
EUR 102
Description: IHC control array containing 3 GIST cases of strong, moderate, weak/nil DOG1 expressers in duplicates

Control for ER, 4 cases (1.5mm)

ERC081 1
EUR 102
Description: IHC control array containing 4 breast cancer cases of strong, moderate, weak/nil estrogen receptor (ER) expressers in duplicates

Control for HER2, 4 cases (1.5mm)

HRC081 1
EUR 102
Description: IHC control array containing 4 breast cancer cases of strong, moderate, low and negative HER2 breast cancer expressers in duplicates

SLLK, Control Peptide for TSP1 Inhibitor

HY-P0301 1mg
EUR 159.6

Control for PR, 3 cases (1.5mm)

PRC061 1
EUR 102
Description: IHC control array containing 3 breast cancer cases of strong, moderate, low/negative progesterone receptor (PR) expressers in duplicates

PAS/Glycogen, For Digestion (Control Slides)

TCS0024-100 100 Slides
EUR 847.2

PAS/Glycogen, For Digestion (Control Slides)

TCS0024-25 25 Slides
EUR 278.4

PAS/Glycogen, For Digestion (Control Slides)

TCS0024-5 5 Slides
EUR 117.6

Thiostatin Rat protein, control for western

TSTN11-C 100 ul
EUR 343.2

Control/Blocking peptide for Human WNT5a

WNT511-P 100 ug
EUR 196.8

Negative Control Antibody for Mouse Monoclonals

V8785-100UG 100ug
EUR 499
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Negative Control Antibody for Mouse Monoclonals

V8785-20UG 20ug
EUR 219
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Negative Control Antibody for Mouse Monoclonals

V8785SAF-100UG 100ug
EUR 499
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.

Eppendorf Centrifuge 5425R Keypad Control With Rotor Refrigerated EU-IVD

E5406000062 EACH
EUR 5434.38

Eppendorf Centrifuge 5425R Keypad Control Without Rotor Refrigerated EU-IVD

E5406000267 EACH
EUR 5055.9

Eppendorf Centrifuge 5425R Knob Control With Rotor Refrigerated EU-IVD

E5406000461 EACH
EUR 5434.38

Eppendorf Centrifuge 5425R Knob Control Without Rotor Refrigerated EU-IVD

E5406000666 EACH
EUR 5055.9

Deer IgG, semi-pure for ELISA (Control, non-immune, isotype control)

20024-2 100 ug
EUR 270

Holder for Plasmid Midi, Maxi and Maxi plus, Ion Exchange column

FAPDE-holder-for-ion-exchange 1 prep
EUR 189.6

AAV1-GFP Control Virus

AAV-301 50 ?L
EUR 1221.6
Description: GFP control virus of AAV serotype 1.

AAV2-GFP Control Virus

AAV-302 50 ?L
EUR 1221.6
Description: GFP control virus of AAV serotype 2.

AAV3-GFP Control Virus

AAV-303 50 ?L
EUR 1221.6
Description: GFP control virus of AAV serotype 3.

AAV4-GFP Control Virus

AAV-304 50 ?L
EUR 1221.6
Description: GFP control virus of AAV serotype 4.

AAV5-GFP Control Virus

AAV-305 50 ?L
EUR 1221.6
Description: GFP control virus of AAV serotype 5.

AAV6-GFP Control Virus

AAV-306 50 ?L
EUR 1221.6
Description: GFP control virus of AAV serotype 6.

AAV2-Cre Control Virus

AAV-310 50 ?L
EUR 1221.6
Description: Cre control virus of AAV serotype 2.

AAV1-Cre Control Virus

AAV-311 50 ?L
EUR 1221.6
Description: Cre control virus of AAV serotype 1.

AAV3-Cre Control Virus

AAV-313 50 ?L
EUR 1221.6
Description: Cre control virus of AAV serotype 3.

AAV4-Cre Control Virus

AAV-314 50 ?L
EUR 1221.6
Description: Cre control virus of AAV serotype 4.

AAV5-Cre Control Virus

AAV-315 50 ?L
EUR 1221.6
Description: Cre control virus of AAV serotype 5.

AAV6-Cre Control Virus

AAV-316 50 ?L
EUR 1221.6
Description: Cre control virus of AAV serotype 6.

AAV2-Luc Control Virus

AAV-320 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 2.

AAV1-Luc Control Virus

AAV-321 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 1.

AAV3-Luc Control Virus

AAV-323 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 3.

AAV4-Luc Control Virus

AAV-324 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 4.

AAV5-Luc Control Virus

AAV-325 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 5.

AAV6-Luc Control Virus

AAV-326 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 6.

scAAV1-GFP Control Virus

AAV-331 50 ?L
EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 1.

scAAV2-GFP Control Virus

AAV-332 50 ?L
EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 2.

scAAV3-GFP Control Virus

AAV-333 50 ?L
EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 3.

scAAV4-GFP Control Virus

AAV-334 50 ?L
EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 4.

scAAV5-GFP Control Virus

AAV-335 50 ?L
EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 5.

scAAV6-GFP Control Virus

AAV-336 50 ?L
EUR 1221.6
Description: Self-complementary GFP control virus of AAV serotype 6.

AAV1-LacZ Control Virus

AAV-341 50 ?L
EUR 1221.6
Description: LacZ control virus of AAV serotype 1.

AAV2-LacZ Control Virus

AAV-342 50 ?L
EUR 1221.6
Description: LacZ control virus of AAV serotype 2.

AAV3-LacZ Control Virus

AAV-343 50 ?L
EUR 1221.6
Description: LacZ control virus of AAV serotype 3.

AAV4-LacZ Control Virus

AAV-344 50 ?L
EUR 1221.6
Description: LacZ control virus of AAV serotype 4.

AAV5-LacZ Control Virus

AAV-345 50 ?L
EUR 1221.6
Description: LacZ control virus of AAV serotype 5.

AAV6-LacZ Control Virus

AAV-346 50 ?L
EUR 1221.6
Description: LacZ control virus of AAV serotype 6.

AAV1 Null Control Virus

AAV-351 50 ?L
EUR 1221.6
Description: Null (empty) control virus of AAV serotype 1.

AAV2 Null Control Virus

AAV-352 50 ?L
EUR 1221.6
Description: Null (empty) control virus of AAV serotype 2.

AAV3 Null Control Virus

AAV-353 50 ?L
EUR 1221.6
Description: Null (empty) control virus of AAV serotype 3.

AAV4 Null Control Virus

AAV-354 50 ?L
EUR 1221.6
Description: Null (empty) control virus of AAV serotype 4.

AAV5 Null Control Virus

AAV-355 50 ?L
EUR 1221.6
Description: Null (empty) control virus of AAV serotype 5.

AAV6 Null Control Virus

AAV-356 50 ?L
EUR 1221.6
Description: Null (empty) control virus of AAV serotype 6.

Bovine Lumpy skin disease virus (LSDV) control for western blot

LSDV11-C 100 ul
EUR 343.2

Recombinant Rat sialodacryoadenitis Virus (SDAV) nucleoprotein control for Western blot

SDAV11-C 100 ul
EUR 343.2

Rabies Virus Glycoprotein (~58 kda, RVG) control for western blot

RBVGP11-C 100 ul
EUR 343.2

Mouse IgG (-ve control for flow cytometry)

20008-1-100 100 tests
EUR 123.6

Rabbit IgG (-ve control for flow cytometry)

20009-1-100 100 tests
EUR 123.6

Human Apolipoprotein B protein control for WB

APOB21-C 100 ul
EUR 343.2

Rec. Human CD21 protein control for WB

CD21-C 100 ul
EUR 343.2

Mouse Ceruloplasmin protein control for western blot

CP16-C 100 ul
EUR 343.2

Rat Ceruloplasmin protein control for western blot

CP17-C 100 ul
EUR 343.2

Bovine Adenosine deaminase protein control for Western

ADA11-C 100 ul
EUR 343.2

Chicken Egg Ovalbumin protein control for Western

OVA11-C 100 ul
EUR 343.2

Mouse negative control sera (purified) for IHC

NCM802M 7 ml
EUR 238.8

Control/Blocking peptide for Ephrin-B2 antibody

NIVE2B-C 100 ug
EUR 196.8

Positive Control for Anti-Rat MEH Antibody

MEHCON 100 uL
EUR 150

Purified bovine Lactoferrin protein control for Western

LTF13-C 100 ul
EUR 343.2

Haptoglobin Human Plasma protein control for WB

HGLB18-C 100 ul
EUR 343.2

Human Hemopexin purified protein control for Western

HPEX11-C 100 ul
EUR 343.2

Hemopexin Mouse, purified protein control for Western

HPEX16-C 100 ul
EUR 343.2

Purified Flagellin (salmonella) protein control for WB

FLGN17-C 100 ul
EUR 343.2

SLLK, Control Peptide for TSP1 Inhibitor(TFA)

HY-P0301A 5mg
EUR 456

Positive Control for Anti-Human CYP1A2 Antibody

P1A2CON 100 uL
EUR 150

Positive Control for Anti-Rat CYP2B1 Antibody

P2B1PTCON 100 uL
EUR 150

Positive Control for Anti-Rat CYP2C Antibody

P2CCON 100 uL
EUR 150

Positive Control for Anti-Rat CYP2D Antibody

P2DCON 100 uL
EUR 150

Positive Control for Anti-Human CYP2E1 Antibody

P2E1PTCON 100 uL
EUR 150

Positive Control for Anti-Rat CYP3A2 Antibody

P3A2PTCON 100 uL
EUR 150

Positive Control for Anti-Human CYP3A Antibody

P3ACON 100 uL
EUR 150

Control Sections for FD NeuroSilver™ Kit

PCS101 each
EUR 69.6

Positive Control for Anti-Human CYP1B1 Antibody

PH1B1CON 100 uL
EUR 150

Purified, Bovine S100 protein control for WB

S1001-C 100 ul
EUR 343.2

Purified, Human S100 protein control for WB

S1002-C 100 ul
EUR 343.2

Control/Blocking peptide for Mouse Vimentin (Vim)

VIM11-C 100 ug
EUR 196.8

Control/Blocking peptide for Human WNT-1

WNT111-P 100 ug
EUR 548.4

Control siRNA Vector (pGB-control)

9500C-20
EUR 405.6

Recombinant Lymphocytic choriomeningitis virus (LCMV) Nucleoprotein (NP) control for Western blot

LCMV14-C 100 ul
EUR 343.2

Purified Pseudorabies Virus glycoprotein B (PsRV gB) control for western blot

PSRVGB11-C 100 ul
EUR 343.2

Recombinant Zika Virus Envelop domain III (African) control for Western blot

ZEND21-C 100 ul
EUR 343.2

Recombinant purified Mouse Pneumonia Virus (PVM) nucleoprotein control for Western blot

PVMNP14-C 100 ul
EUR 343.2

pRedZeo-CMV Virus [positive control]

SR10046VA-1 >2 x 10^6 IFUs
EUR 826.8

pRedTK-CMV Virus [positive control]

SR10052VA-1 >2 x 10^6 IFUs
EUR 826.8

pGreenZeo-mCMV Virus [negative control]

SR500VA-1 >2 x 10^6 IFUs
EUR 806.4

pGreenZeo-CMV Virus [positive control]

SR501VA-1 >2 x 10^6 IFUs
EUR 806.4

Human Apolipoprotein C-I protein control for WB

APOC11-C 100 ul
EUR 343.2

Human Apolipoprotein C-II protein control for WB

APOC22-C 100 ul
EUR 343.2

Human Apolipoprotein C-III protein control for WB

APOC32-C 100 ul
EUR 343.2

Human plasma Apolipoprotein E protein control for WB

APOE13-C 100 ul
EUR 343.2

Human Plasma Apolipoprotein J protein control for WB

APOJ13-C 100 ul
EUR 343.2

Chicken Serum Albumin protein control for Western blot

ALBC15-C 100 ul
EUR 343.2

Monkey (Rhesus) Serum Albumin protein control for WB

ALBMK21-C 100 ul
EUR 343.2

Monkey (Rhesus) Serum Albumin protein control for WB

ALBMK22-C 100 ul
EUR 343.2

Recombinant Beta Lactamase protein control for Western blot

BLAC11-C 100 ul
EUR 343.2

Purified human Catalase (CATL) protein control for WB

CATL11-C 100 ul
EUR 343.2

Positive Control for Anti-Human Cytochrome b5 Antibody

Cb5CON 100 uL
EUR 150

Chicken Egg yellow proteins total control for Western

CEYP12-C 100 ul
EUR 343.2

Purified Cholera Toxin protein control for Western Blot

CTOX11-C 100 ul
EUR 343.2

Chicken Egg Conalbumin (ovotransferrin) protein control for Western

CECA15-C 100 ul
EUR 343.2

Chicken Egg white proteins total control for Western

CEGW12-C 100 ul
EUR 343.2

Chicken Ovomucoid (trypsin inhibitor) protein control for Western

COVM13-C 100 ul
EUR 343.2

Rabbit Beta Actin (muscle) protein control for Western

ACTB15-C 100 ul
EUR 388.8

Myoglobin, Human Cardiac, purified protein control for western

MYG17-C 100 ul
EUR 343.2

Purified Lassa fever Nucleoprotein control for Western Blotting

LFNP15-C-10 100 ul
EUR 343.2

Control/Blocking peptide for Mouse Histone deacetylase 1

HDAC111-P 100 ug
EUR 196.8

Purified Human Neutrophil Elastase protein control for WB

ESTE11-C 100 ul
EUR 343.2

Positive Control for Anti-Rat CYP1A1/1A2 Antibody

P1ACON 100 uL
EUR 150

Positive Control for Anti-Rat CHP2B1/2 Antibody

P2B12PTCON 100 uL
EUR 150

Human Prothrombin (Factor II) protein control for Western

PRTN11-C 100 ul
EUR 343.2

Mouse Prothrombin (Factor II) protein control for Western

PRTN13-C 100 ul
EUR 343.2

Control sections for FD NeuroApop™ Kit (frozen)

PCS102- each
EUR 87.6

Control sections for FD NeuroApop™ Kit (paraffin)

PCS102-1 each
EUR 80.44
Description: Best quality products

Control sections for FD NeuroApop™ Kit (frozen)

PCS102-2 each
EUR 80.54
Description: Best quality products

Human Pancreatic Amylase protein control for Western blot

PAMY13-C 100 ul
EUR 343.2

Human Salivary Amylase protein positive control for WB

SAMY16-C 100 ul
EUR 343.2

Purified, recombinant Human TACE control protein for WB

TACE11-C 100 ul
EUR 343.2

Purified Human Survivin protein for WB +ve control

SURV11-C 100 ul
EUR 343.2

Quality Control

abx098966-1vial 1 vial
EUR 360

pMD18- Control

PVT10563 2 ug
EUR 319.2

pMD19- Control

PVT10564 2 ug
EUR 319.2

Recombinant African Swine fever virus (ASFV) P30 protein control for western blot

ASFV11-C 100 ul
EUR 343.2

Bovine Viral Diarrhea Virus 1 (BVDV1) Erns Protein control for western blot

BVDR12-C 100 ul
EUR 343.2

Recombinant Zaire-Ebola virus nucleoprotein (Mayinga EBOV NP) protein control for Western

EVNP11-C 100 ul
EUR 343.2

Recombinant (E.Coli) Japanese Encephalitis Virus (JEV) prM protein control for Western blot

JEV13-C 100 ul
EUR 343.2

Recombinant (HEK) Rift Valley Fever Virus NP protein control for Western blot

RVFNP12-C 100 ul
EUR 343.2

Recombinant (sf9) Purified Sudan-Ebola virus glycoprotein protein control for Western Blot

SVGP21-C 100 ul Ask for price

Recombinant (E. coli) Zika Virus Envelop Protein (African) control for Western blot

ZENV11-C 100 ul
EUR 343.2

Recombinant (E. coli) Zika Virus NS1 Protein (African) control for Western blot

ZNS111-C 100 ul
EUR 343.2

Ivd/ Rat Ivd ELISA Kit

ELI-39421r 96 Tests
EUR 1063.2

Recombinant Polyoma Virus (KV, Pneumotropic virus) Capsid Protein 1 (VP1) control for Western blot

KVP14-C 100 ul
EUR 343.2

NATtrol BK Virus External Run Control, Low (6 X 1 mL)

NATBK-ERCL 6 X 1 mL
EUR 406.94
Description: Please contact Gentaur in order to receive the datasheet of the product.

NATtrol BK Virus External Run Control, Medium (6 X 1 mL)

NATBK-ERCM 6 X 1 mL
EUR 481.82
Description: Please contact Gentaur in order to receive the datasheet of the product.

Rat neurofascin (Nfasc)-control Control/blocking peptide

AB-23249-CP 100ug
EUR 196.8

Alpha 2-Macroglobulin (A2M), Human protein control for WB

A2MG11-C 100 ul
EUR 343.2

Alpha-1-Acid Glycoprotein Protein, Dog, control for western

A1AG17-C 100 ul
EUR 343.2

Alpha-1-Acid Glycoprotein Protein, Mouse, control for western

A1AG18-C 100 ul
EUR 343.2

Alpha 1-Antitrypsin (A1AT), Human protein control for WB

A1AT11-C 100 ul
EUR 343.2

Apolipoprotein A-Il, Human Plasma protein control for WB

APOA21-C 100 ul
EUR 343.2

Purified Mouse serum albumin protein control for Western blot

ALB11-C 100 ul
EUR 343.2

Purified Human serum albumin protein control for Western blot

ALBH13-C 100 ul
EUR 343.2

Purified rat serum albumin protein control for Western blot

ALBR12-C 100 ul
EUR 343.2

Purified Sheep serum albumin protein control for Western blot

ALBSH20-C 100 ul
EUR 343.2

Recombinant human BAFF-R protein control for Western blot

BAFFR11-C 100 ul
EUR 343.2

Human recombinant purified BMP-1 protein control for WB

BMP12-C 100 ul
EUR 343.2

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC041520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF405S conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNC041520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),CF405S conjugate, Concentration: 0.1mg/mL

Human Liver Cathepsin B protein control for Western blot

CTHB11-C 100 ul
EUR 343.2

Human Liver Cathepsin D protein control for Western blot

CTHD11-C 100 ul
EUR 343.2

Human Liver Cathepsin G protein control for Western blot

CTHG11-C 100 ul
EUR 343.2

Human Liver Cathepsin H protein control for Western blot

CTHH11-C 100 ul
EUR 343.2

Human Liver Cathepsin L protein control for Western blot

CTHL11-C 100 ul
EUR 343.2

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCAP1520-100 100uL
EUR 238.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R) Antibody

BNCAP1520-500 500uL
EUR 652.8
Description: Primary antibody against Negative Control for Rabbit Monoclonal Antibodies (NCRBM/1520R),Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Results: We identified four network modules with statistical significance (P <0.05), two of which are connected to the PASI score, while the other two are connected to the 8-week treatment and ΔPASI. In patients with psoriasis, inflammatory pathway and inhibit activated G-protein signaling genes (GTPase IMAP family members and the G protein-coupled receptors) co-occur, including high expression of CD83 and CD69 and low expression of CD160 and CD180, compared to healthy controls.

Accompanying LJD treatment and remission of lesions, the expression of CD69 and associated cell cycle genes including CCNA2, CCNB2, Cdk1, and TOP2A down-regulated. LJD inhibitory role on CD69 expression was confirmed by activating naive CD4 + T lymphocytes

Conclusions: Our study suggests that psoriasis is marked with immune status is not balanced with dendritic cell activation and inflammation associated lymphocytes as well as NK-cells and B cell-related defense response aberrance. LJD play a role in the inhibition of T cell activation, a process which is located downstream of the pathological cascade of psoriasis.

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